Matsuzaki T, Otose H, Hashimoto K, Shibata Y, Arimura K, Osame M
Third Department of Internal Medicine, Faculty of Medicine, Kagoshima University, Japan.
Intern Med. 1993 Aug;32(8):623-8. doi: 10.2169/internalmedicine.32.623.
The health effects of human T-lymphotropic virus type I (HTLV-I) were studied in HTLV-I endemic areas in Japan during the period from September 1990 to October 1991. The study subjects were 2,847 men living in the southern part of Kyushu and engaged in light work. Ages ranged from 19 to 79 years (47.8 +/- 7.2; mean +/- standard deviation). The prevalence of each disturbance was analyzed with a logistic model. The disturbances in which the prevalence showed a significant association with HTLV-I were old tuberculosis, ulcerative colitis and ossification of the posterior longitudinal ligament of the cervical spine (OPLL). The results of the present study suggest that HTLV-I may be a risk factor for these diseases and may indicate the necessity for a synthetic study on HTLV-I.
1990年9月至1991年10月期间,在日本人类嗜T淋巴细胞病毒I型(HTLV-I)流行地区,对HTLV-I的健康影响进行了研究。研究对象为居住在九州南部、从事轻体力劳动的2847名男性。年龄范围为19至79岁(平均47.8±7.2岁;均值±标准差)。采用逻辑模型分析每种疾病的患病率。患病率与HTLV-I呈显著关联的疾病有陈旧性肺结核、溃疡性结肠炎和颈椎后纵韧带骨化(OPLL)。本研究结果表明,HTLV-I可能是这些疾病的一个危险因素,可能意味着有必要对HTLV-I进行综合研究。