Golbs S, Fuchs V, Leipner E, Hüttel I
Arch Exp Veterinarmed. 1978;32(4):569-77.
After oral administration of pesticides Parathion-methyl, Carbaryl, Lindane and their combinations were investigated the activities of enzyme SGOT, SGPT, Alkaline Phosphatase and Cholinesterase. Results concerning SGOT-activity demonstrated a significant increase in all groups. The cause of this rise can be found in its effect on liver, muscle and/or heart. The activity of cholinesterase is significantly lower in the combinations of Parathion-methyl/Lindane, Lindane/Carbaryl and Carbaryl/Parathion-methyl. In future the extent of these investigations concerning the subacute toxicity, chronical toxicity, the additive or cumulative effects of pesticide--combinations, combinations of pesticides with drugs and/or xenobiotics etc. must be enhanced in any case.
口服甲基对硫磷、西维因、林丹及其组合农药后，研究了血清谷草转氨酶（SGOT）、血清谷丙转氨酶（SGPT）、碱性磷酸酶和胆碱酯酶的活性。关于SGOT活性的结果表明，所有组均有显著升高。这种升高的原因可归因于其对肝脏、肌肉和/或心脏的影响。在甲基对硫磷/林丹、林丹/西维因和西维因/甲基对硫磷的组合中，胆碱酯酶的活性显著降低。今后，无论如何都必须加强对这些农药组合的亚急性毒性、慢性毒性、相加或累积效应、农药与药物和/或外源性物质等组合的研究。
