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[α-生育酚和烟酰胺对早产大鼠幼崽肺组织脂质过氧化及抗氧化系统活性的影响]

[The effect of alpha-tocopherol and nicotinamide on lipid peroxidation and the activity of the antioxidant system in the lung tissue of premature rat pups].

作者信息

Nadzhimutdinov K N, Mavlianov I R, Umarov E F, Mutalov N K

出版信息

Eksp Klin Farmakol. 1993 Sep-Oct;56(5):28-30.

PMID:8312804
Abstract

The antenatal use of nicotinamide and especially alpha-tocopherol in the experiments with premature newborn rats caused a significant decrease in the rate of lipid peroxidation and an increase in catalase activity both in the maternal body and in fetal lung tissue. It is suggested that the drugs can be used to prevent the development of membrane-destructive processes in the fetal and neonatal lung.

摘要

在早产新生大鼠实验中,产前使用烟酰胺尤其是α-生育酚,导致母体及胎儿肺组织中脂质过氧化速率显著降低,过氧化氢酶活性增加。提示这些药物可用于预防胎儿和新生儿肺中膜破坏过程的发展。

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Eksp Klin Farmakol. 1993 Sep-Oct;56(5):28-30.
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Effects of maternal vitamin E and selenium status during the perinatal period on age-related changes in tissue concentration of vitamin E in rat pups.围产期母体维生素E和硒状态对幼鼠组织中维生素E浓度与年龄相关变化的影响。
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Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation.
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