Hülskamp M, Misŕa S, Jürgens G
Institut für Genetik und Mikrobiologie, Universität München, Federal Republic of Germany.
Cell. 1994 Feb 11;76(3):555-66. doi: 10.1016/0092-8674(94)90118-x.
Trichomes are specialized epidermal cells that are regularly distributed on the leaves of Arabidopsis plants. During leaf development, each trichome undergoes cell morphogenesis, resulting in a very precise architecture. We have isolated and characterized more than 70 trichome mutants that represent 21 different genes. By analyzing their cellular phenotypes, it has been possible to define specific steps in trichome development. Although these steps normally occur in a temporal sequence, genetic dissection indicates that the morphology of the mature cell is largely assembled in independent events. The results suggest a model of how a specialized cell type originates from a uniform cell layer.
毛状体是拟南芥植物叶片上规则分布的特化表皮细胞。在叶片发育过程中，每个毛状体都会经历细胞形态发生，从而形成非常精确的结构。我们已经分离并鉴定了70多个代表21个不同基因的毛状体突变体。通过分析它们的细胞表型，已经有可能确定毛状体发育中的特定步骤。虽然这些步骤通常按时间顺序发生，但遗传剖析表明，成熟细胞的形态在很大程度上是在独立事件中组装而成的。这些结果提出了一种关于特殊细胞类型如何从均匀细胞层起源的模型。
