Collier P M, James M P
Department of Dermatology, Royal Berkshire Hospital, Reading, UK.
Clin Exp Dermatol. 1994 Jan;19(1):61-4. doi: 10.1111/j.1365-2230.1994.tb01119.x.
The cases of two brothers who both developed pseudopelade at the age of 7 years, with progressive patchy hair loss, are reported. Biopsy in the elder brother showed typical changes with reduced numbers of hair follicles and sebaceous glands, a sparse lymphocytic infiltrate and an absence of widespread scarring. A third family member may have been affected. The absence of a family history in most cases suggests our patients may have a different aetiology. This report of two, possibly three, family members with pseudopelade suggests genetic factors may play a role in this family. Pseudopelade is very rare in children and we are not aware of any reports of familial occurrence. Atrophy rather than scarring is the primary feature of this condition and pseudopelade of Brocq should not be classified as a cicatricial alopecia.
报道了两兄弟的病例，他们均在7岁时患上假性斑秃，伴有进行性斑片状脱发。哥哥的活检显示出典型变化，毛囊和皮脂腺数量减少，淋巴细胞浸润稀疏，且无广泛瘢痕形成。第三名家庭成员可能也受到了影响。大多数病例无家族病史，这表明我们的患者可能有不同的病因。这份关于两名（可能三名）患有假性斑秃的家庭成员的报告表明，遗传因素可能在这个家族中起作用。假性斑秃在儿童中非常罕见，我们不知道有任何家族性发病的报道。萎缩而非瘢痕形成是这种疾病的主要特征，布罗克假性斑秃不应归类为瘢痕性脱发。
