Ruffolo T A, Sherman S, Lehman G A, Hawes R H
Indiana University Hospital, Indianapolis 46202-5244.
Dig Dis Sci. 1994 Feb;39(2):289-92. doi: 10.1007/BF02090199.
Theoretically, relative distal common bile duct obstruction due to sphincter of Oddi dysfunction may be a cause of poor gallbladder evacuation observed on quantitative cholescintigraphy. In this study, the relationship of sphincter of Oddi dysfunction to the gallbladder ejection fraction by quantitative cholescintigraphy was explored. Eighty-one patients with biliary-type pain and otherwise normal evaluations underwent quantitative cholescintigraphy, sphincter of Oddi manometry, and ERCP. Abnormalities of stimulated quantitative cholescintigraphy and/or sphincter of Oddi manometry were present in 70% of this study group. Manometric evidence of sphincter dysfunction was present in patients with similar frequency irrespective of the degree of gallbladder evacuation. In conclusion, abnormalities of quantitative cholescintigraphy and sphincter manometry appear to be independent factors, although frequent findings in this patient population.
理论上，由于Oddi括约肌功能障碍导致的相对远端胆总管梗阻可能是定量胆囊闪烁造影中观察到胆囊排空不良的一个原因。在本研究中，探讨了Oddi括约肌功能障碍与定量胆囊闪烁造影测得的胆囊射血分数之间的关系。81例有胆源性疼痛且其他评估正常的患者接受了定量胆囊闪烁造影、Oddi括约肌测压和内镜逆行胰胆管造影（ERCP）。该研究组中70%存在刺激后定量胆囊闪烁造影和/或Oddi括约肌测压异常。无论胆囊排空程度如何，括约肌功能障碍的测压证据在患者中出现的频率相似。总之，定量胆囊闪烁造影和括约肌测压异常似乎是独立因素，尽管在该患者群体中经常出现这些发现。
