齐多夫定联合α-2b干扰素治疗HIV感染合并慢性活动性病毒性肝炎患者。
Zidovudine plus interferon alfa-2b treatment in patients with HIV and chronic active viral hepatitis.
作者信息
Visco G, Alba L, Grisetti S, Guarascio P, Narciso P, Sette P, Struglia C, Tossini G, Tozzi V
机构信息
L. Spallanzani Hospital for Infectious Diseases, Rome, Italy.
出版信息
Gut. 1993;34(2 Suppl):S107-8. doi: 10.1136/gut.34.2_suppl.s107.
Results are reported for a small study of 11 patients positive for HIV and with chronic active viral hepatitis. Low dose zidovudine/interferon alfa-2b combined treatment produced a general reduction in alanine aminotransferase activities and increased the CD4 lymphocyte count, hepatitis B e seroconversion, and the loss of HIV p24 antigen. The treatment was well tolerated and progression of HIV disease was not seen.
报告了一项针对11名HIV阳性且患有慢性活动性病毒性肝炎患者的小型研究结果。低剂量齐多夫定/干扰素α-2b联合治疗使丙氨酸转氨酶活性普遍降低，增加了CD4淋巴细胞计数、乙肝e抗原血清转换以及HIV p24抗原的消失。该治疗耐受性良好，未观察到HIV疾病进展。
Zotero 插件