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以色列人群中弓形虫感染的血清流行病学研究。

Seroepidemiology of Toxoplasma gondii infection in the Israeli population.

机构信息

Israel Center for Diseases Control, Israel Ministry of Health, Tel-Hashomer, Israel.

出版信息

Epidemiol Infect. 2014 Jan;142(1):149-55. doi: 10.1017/S0950268813000903. Epub 2013 Apr 15.

DOI:10.1017/S0950268813000903
PMID:23587449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9152547/
Abstract

Toxoplasmosis seroprevalence varies considerably between countries. We studied the seroprevalence of Toxoplasma gondii IgG antibodies in a national sample of the Israeli population; 2794 sera were tested. The highest age-adjusted seroprevalence rate was in Arabs (non-Bedouins) (60.4%), significantly higher compared to the rate in Jews (19.9%) and Bedouins (27.5%) (P < 0.01). There were no significant gender differences. Seropositivity increased with age in all population groups. For Jews, seropositivity was associated with place of birth and socioeconomic status. A finding of low seroprevalence rate in Bedouins despite their poor living conditions and close contact with livestock is surprising, and might be attributed to the dry and hot climate conditions in their area of residence. In women of reproductive age the seroprevalence was 15.1% in Jews, 25.4% in Bedouins and 72.3% in Arabs (non-Bedouins). Thus, the majority of pregnant women are susceptible to primary infection with T. gondii, and the risk for congenital toxoplasmosis remains high.

摘要

弓形虫病血清阳性率在各国之间差异很大。我们研究了以色列全国人群中弓形虫 IgG 抗体的血清阳性率;检测了 2794 份血清。阿拉伯人(非贝都因人)的年龄调整后血清阳性率最高(60.4%),与犹太人(19.9%)和贝都因人(27.5%)的比率相比显著更高(P<0.01)。性别之间没有显著差异。所有人群的血清阳性率均随年龄增长而增加。对于犹太人,血清阳性率与出生地和社会经济地位有关。尽管贝都因人的生活条件较差且与牲畜密切接触,但他们的血清阳性率较低,这一发现令人惊讶,这可能归因于他们居住地的干燥炎热的气候条件。在育龄妇女中,犹太人的血清阳性率为 15.1%,贝都因人的血清阳性率为 25.4%,阿拉伯人(非贝都因人)的血清阳性率为 72.3%。因此,大多数孕妇容易受到弓形虫的初次感染,先天性弓形虫病的风险仍然很高。

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