Vander Griend R A, Funderburk C H
Department of Orthopaedics, University of Florida, Gainesville 32610-0246.
J Bone Joint Surg Am. 1993 Jun;75(6):899-908. doi: 10.2106/00004623-199306000-00011.
We reviewed the results of the treatment of giant-cell tumors of the distal part of the radius in twenty-three patients, to identify criteria that could assist in the selection of the most effective option for treatment or reconstruction. The treatment was chosen on the basis of the preoperative roentgenographic assessment of the extent of the tumor. Seven patients, who had received previous treatment elsewhere, were referred to us because of a local recurrence. An extended curettage followed by packing of the cavity with cement was effective in preserving the normal function of the extremity and in eradicating the lesion in five patients who had a lesion that was intraosseous or that involved minimum cortical perforation. Of the eighteen remaining patients, who had extraosseous extension of the tumor, seventeen had a resection of the distal part of the radius and one had a below-the-elbow amputation. After resection of the involved segment of bone, the best functional result was seen in the patients who had been managed with a radiocarpal arthrodesis and use of an intercalary bone graft that was stabilized with a long plate. At the most recent follow-up examination (range, two to nineteen years after the curettage or resection), there had been no local recurrences.
我们回顾了23例桡骨远端骨巨细胞瘤的治疗结果,以确定有助于选择最有效治疗或重建方案的标准。治疗方案是根据术前对肿瘤范围的X线评估来选择的。7例曾在其他地方接受过治疗的患者因局部复发被转诊至我们这里。对于5例病变位于骨内或仅涉及最小皮质穿孔的患者,采用扩大刮除术并随后用骨水泥填充骨腔,有效地保留了肢体的正常功能并根除了病变。其余18例肿瘤有骨外扩展的患者中,17例行桡骨远端切除术,1例行肘下截肢术。在切除受累骨段后,采用桡腕关节融合术并使用长钢板固定的间置骨移植治疗的患者功能恢复最佳。在最近的随访检查中(刮除或切除术后2至19年),未出现局部复发。