Hamasaki K, Hamasaki H, Kashimura M, Fujimoto S
Division of Maternal Health, School of Nursing, University of Occupational and Environmental Health, Fukuoka.
Nihon Sanka Fujinka Gakkai Zasshi. 1993 Jun;45(6):547-50.
The immunocytochemical localization of hCG in the syncytiotrophoblast of hydatidiform moles was observed by means of the immunoglobulin gold technique with rabbit anti-human hCG serum. Immunoreactive gold particles of hCG are preferentially localized in the distal portion of the Golgi complexes, Golgi-derived secretory granules 200-300 nm in diameter, and large electron dense bodies 500-1,000 nm in diameter. The secretory granules exist throughout the cytoplasm above the nuclear region and are occasionally released by exocytosis from the syncytiotrophoblast. On the other hand, the large electron dense granules seem to be cytolysosomes in nature and are involved in uptake and storage of hCG.
采用兔抗人绒毛膜促性腺激素（hCG）血清的免疫球蛋白金技术，观察了葡萄胎合体滋养层细胞中hCG的免疫细胞化学定位。hCG的免疫反应性金颗粒优先定位于高尔基体复合体的远端、直径为200 - 300nm的高尔基体衍生分泌颗粒以及直径为500 - 1000nm的大电子致密体中。分泌颗粒存在于核区上方的整个细胞质中，偶尔通过合体滋养层细胞的胞吐作用释放。另一方面，大电子致密颗粒本质上似乎是细胞溶酶体，参与hCG的摄取和储存。
