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一名原住民的热带痉挛性截瘫

Tropical spastic paraparesis in an aborigine.

作者信息

Rajabalendaran N, Burns R, Mollison L C, Blessing W, Kirubakaran M G, Lindschau P

机构信息

Department of Medicine, Alice Springs Hospital, NT.

出版信息

Med J Aust. 1993 Jul 5;159(1):28-9. doi: 10.5694/j.1326-5377.1993.tb137700.x.

Abstract

OBJECTIVE

To present the first documented case of human T-lymphotropic virus type I (HTLV-I) associated myelopathy/tropical spastic paraparesis in the Australian population.

CLINICAL FEATURES

A 31-year-old Aboriginal man with an 18-month history of progressive weakness of the legs was found to have an upper motor neurone weakness of all limbs associated with sphincteric disturbance and impotence. HTLV-I antibodies were detected in his serum and no other cause for the patient's myelopathy could be found.

INTERVENTION AND OUTCOME

He was counselled regarding HTLV-I associated myelopathy/tropical spastic paraparesis.

CONCLUSION

This is the first description of HTLV-I associated myelopathy/tropical spastic paraparesis in an Australian. In cases of spinal cord disorder without evidence of compression we recommend serological testing for HTLV-I, especially in Aboriginal patients. Additionally, testing of blood donors for this retrovirus needs consideration.

摘要

目的

报告澳大利亚人群中首例有文献记载的1型人类嗜T淋巴细胞病毒(HTLV-I)相关脊髓病/热带痉挛性截瘫病例。

临床特征

一名31岁的原住民男性,有18个月腿部进行性无力病史,发现四肢存在上运动神经元性无力,并伴有括约肌功能障碍和阳痿。其血清中检测到HTLV-I抗体,未发现该患者脊髓病的其他病因。

干预措施及结果

就HTLV-I相关脊髓病/热带痉挛性截瘫对其进行了咨询。

结论

这是澳大利亚首例HTLV-I相关脊髓病/热带痉挛性截瘫的描述。对于无压迫证据的脊髓疾病病例,我们建议进行HTLV-I血清学检测,尤其是在原住民患者中。此外,需要考虑对献血者进行这种逆转录病毒的检测。

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