Klein M, Grishman E
Arch Dermatol. 1977 Jan;113(1):64-8.
A patient had a primary cutaneous plasmacytoma of the cheek. Histologic studies showed dense aggregates of plasma cells admixed with occasional histiocytes. The cytoplasm of the histiocytes contained needle-like structures. Electron microscopy showed these structures to be completely enclosed within smooth membranes. They often were rhombic, with occasional broken-off corners. It is hypothesized that these structures represent protein that has been secreted by the plasma cells and subsequently phagocytosed and stored in crystalloid form by the neighboring histiocytes. The patient is asymptomatic 1 1/2 years after removal of the tumor.
一名患者患有脸颊原发性皮肤浆细胞瘤。组织学研究显示浆细胞密集聚集，偶尔混有组织细胞。组织细胞的细胞质中含有针状结构。电子显微镜显示这些结构完全被光滑膜包裹。它们通常呈菱形，偶尔有角断裂。据推测，这些结构代表浆细胞分泌的蛋白质，随后被邻近的组织细胞吞噬并以晶体形式储存。肿瘤切除1年半后，患者无症状。
