Vital A, Vital C, Ellie E, Ferrer X, Lagueny A, Ferrer A M, Broustet A, Gbikpi-Benissan G
Department of Neuropathology, Bordeaux Hospital, France.
Neuropathol Appl Neurobiol. 1993 Apr;19(2):159-63. doi: 10.1111/j.1365-2990.1993.tb00422.x.
Two patients suffering from acute myelomonoblastic leukaemia developed clinical evidence of peripheral nerve involvement. In both cases, a peripheral nerve biopsy revealed endoneurial cellular infiltrates which were identified as leukaemic cells by immunocytochemistry. Ultrastructural studies showed mainly axonal damage. Moreover, in one patient, a few features of active demyelination were also observed.
两名急性粒单核细胞白血病患者出现了周围神经受累的临床证据。在这两个病例中，周围神经活检显示神经内膜有细胞浸润，免疫细胞化学鉴定这些浸润细胞为白血病细胞。超微结构研究主要显示轴突损伤。此外，在一名患者中，还观察到一些活跃脱髓鞘的特征。
