• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

低剂量氯法齐明引起的严重腹痛

Severe abdominal pain in low dosage clofazimine.

作者信息

Chong P Y, Ti T K

机构信息

Department of Pathology, National University Hospital, National University of Singapore.

出版信息

Pathology. 1993 Jan;25(1):24-6. doi: 10.3109/00313029309068897.

DOI:10.3109/00313029309068897
PMID:8316494
Abstract

We describe a 41 yr old leprosy patient treated for 10 yrs with clofazimine who underwent laparotomy for severe abdominal pain. At surgery, the only significant findings were that the coeliac lymph nodes were enlarged and stained purplish black as were the omentum and the intraperitoneal fat. No other cause of abdominal pain was identified. On histological examination, reddish-purple crystals were identified at frozen section but not in the paraffin sections.

摘要

我们描述了一名41岁的麻风病患者,他用氯法齐明治疗了10年,因严重腹痛接受了剖腹手术。手术中,唯一显著的发现是腹腔淋巴结肿大,大网膜和腹膜内脂肪呈紫黑色。未发现其他腹痛原因。组织学检查显示,冰冻切片中发现了红紫色晶体,但石蜡切片中未发现。

相似文献

1
Severe abdominal pain in low dosage clofazimine.低剂量氯法齐明引起的严重腹痛
Pathology. 1993 Jan;25(1):24-6. doi: 10.3109/00313029309068897.
2
Clofazimine-induced crystal-storing histiocytosis producing chronic abdominal pain in a leprosy patient.氯法齐明诱发的晶体贮积性组织细胞增多症导致一名麻风病患者出现慢性腹痛。
Am J Surg Pathol. 2000 Jan;24(1):129-35. doi: 10.1097/00000478-200001000-00016.
3
Clofazimine-induced enteropathy in a patient of leprosy.氯法齐明致麻风病患者肠病。
Indian J Pharmacol. 2013 Mar-Apr;45(2):197-8. doi: 10.4103/0253-7613.108323.
4
Intra-abdominal, crystal-storing histiocytosis due to clofazimine in a patient with lepromatous leprosy and concurrent carcinoma of the colon.氯法齐明致瘤型麻风并发结肠癌患者出现腹腔内晶体贮积性组织细胞增多症
Lepr Rev. 2004 Jun;75(2):171-6.
5
Effect of clofazimine on eye in multibacillary leprosy.
Indian J Lepr. 1990 Jan-Mar;62(1):87-90.
6
Side effects of clofazimine therapy.
Lepr India. 1976 Oct;48(4 Suppl):722-31.
7
More about clofazimine--3 years experience and review of literature.关于氯法齐明的更多内容——3年经验及文献综述
Indian J Lepr. 1987 Jan-Mar;59(1):63-74.
8
Effect of clofazimine: detailed studies of small intestine functions.
Indian J Lepr. 1985 Apr-Jun;57(2):364-72.
9
Splenic infarction and tissue accumulation of crystals associated with the use of clofazimine (Lamprene; B663) in the treatment of pyoderma gangrenosum.使用氯法齐明(Lamprene;B663)治疗坏疽性脓皮病时出现的脾梗死及晶体组织蓄积。
Br J Dermatol. 1980 Feb;102(2):227-30. doi: 10.1111/j.1365-2133.1980.tb05697.x.
10
[Small intestine transit anomalies in a patient with chronic abdominal pain and treated for Hansen's disease].[一名慢性腹痛且接受过麻风病治疗患者的小肠转运异常]
J Radiol. 1986 Mar;67(3):213-8.

引用本文的文献

1
Clofazimine for the treatment of tuberculosis.氯法齐明用于治疗结核病。
Front Pharmacol. 2023 Feb 2;14:1100488. doi: 10.3389/fphar.2023.1100488. eCollection 2023.
2
Clofazimine-induced enteropathy in a patient of leprosy.氯法齐明致麻风病患者肠病。
Indian J Pharmacol. 2013 Mar-Apr;45(2):197-8. doi: 10.4103/0253-7613.108323.