Armstrong T J, Buckle P, Fine L J, Hagberg M, Jonsson B, Kilbom A, Kuorinka I A, Silverstein B A, Sjogaard G, Viikari-Juntura E R
Center for Ergonomics, University of Michigan, Ann Arbor 48109-2117.
Scand J Work Environ Health. 1993 Apr;19(2):73-84. doi: 10.5271/sjweh.1494.
This paper presents a conceptual model for the pathogenesis of work-related musculoskeletal disorders. The model contains sets of cascading exposure, dose, capacity, and response variables, such that response at one level can act as dose at the next. Response to one or more doses can diminish or increase the capacity for responding to successive doses. The model is used as a framework for discussing the development of work-related muscle, tendon, and nerve disorders. It is intended as a beginning, to be modified to explain new findings as they become available. In research, it can help to identify areas needing additional data for the development and expression of work-related musculoskeletal disorders. Researchers can use it to design laboratory and field studies. In practice, it demonstrates the relationship between common exposure factors and different responses. This information can be used to evaluate and design jobs for the prevention of work-related musculoskeletal disorders.
本文提出了一个与工作相关的肌肉骨骼疾病发病机制的概念模型。该模型包含一系列级联的暴露、剂量、能力和反应变量，使得一个层面的反应可以作为下一层面的剂量。对一个或多个剂量的反应可以降低或增加对后续剂量作出反应的能力。该模型用作讨论与工作相关的肌肉、肌腱和神经疾病发展情况的框架。它旨在作为一个起点，随着新发现的出现进行修改以解释这些新发现。在研究中，它有助于确定与工作相关的肌肉骨骼疾病的发展和表现所需额外数据的领域。研究人员可以用它来设计实验室和现场研究。在实践中，它展示了常见暴露因素与不同反应之间的关系。这些信息可用于评估和设计工作，以预防与工作相关的肌肉骨骼疾病。
