Walsh J M, Baron R B, Browner W S
Division of General Internal Medicine, University of California, School of Medicine, San Francisco.
West J Med. 1993 Apr;158(4):359-63.
We compared current practice with the National Cholesterol Education Program (NCEP) guidelines for the detection and evaluation of hypercholesterolemia and analyzed the association of various patient and provider factors with screening. Using a retrospective medical records review of 1,000 randomly selected patients between the ages of 18 and 70 in a university-based general internal medicine practice--faculty, residents (categorical and primary care), and nurse practitioners--we found that 80% of patients were screened for hypercholesterolemia. Patients older than 35 were more likely to be screened than younger patients (87% versus 77%; P = .001), and, among younger patients, nonwhites were less likely to be screened than whites (58% versus 77%; P = .0001). Lipoprotein analysis was done in 60% of the 235 patients in whom it was indicated; older patients were significantly more likely to have these measurements. Among patients taking medications for hypercholesterolemia, 92% had lipoprotein analyses done beforehand. No differences were detected in screening by provider characteristics. We conclude that providers in our practice are appropriately aggressive in screening high-risk patients for hypercholesterolemia. The finding that young whites are screened much more often than nonwhites was surprising. Finally, although there is a high rate of screening overall, many patients with elevated cholesterol levels are not appropriately classified as to their low-density-lipoprotein levels.
我们将当前的做法与美国国家胆固醇教育计划(NCEP)关于高胆固醇血症检测和评估的指南进行了比较,并分析了各种患者和医疗服务提供者因素与筛查之间的关联。通过对一所大学附属普通内科诊所(包括教员、住院医师(分类和初级保健)以及执业护士)中随机选取的1000名年龄在18至70岁之间的患者进行回顾性病历审查,我们发现80%的患者接受了高胆固醇血症筛查。35岁以上的患者比年轻患者更有可能接受筛查(87%对77%;P = .001),而且在年轻患者中,非白人比白人接受筛查的可能性更小(58%对77%;P = .0001)。在235名有指征的患者中,60%进行了脂蛋白分析;老年患者进行这些检测的可能性明显更高。在服用高胆固醇血症药物的患者中,92%事先进行了脂蛋白分析。未发现筛查在医疗服务提供者特征方面存在差异。我们得出结论,我们诊所的医疗服务提供者在筛查高风险患者的高胆固醇血症方面采取了适当积极的措施。年轻白人比非白人接受筛查的频率高得多这一发现令人惊讶。最后,尽管总体筛查率很高,但许多胆固醇水平升高的患者在低密度脂蛋白水平方面没有得到适当分类。