Lupa K, Kruk A, Wójcik G, Tarnecki R, Niechaj A
Department of Human Physiology, Medical School, Lublin, Poland.
Acta Neurobiol Exp (Wars). 1993;53(1):183-6.
The pattern of inhibitory responses of sympathetic nerve discharge to liminal activation of aortic C-fibres was studied in rabbits. The animals were anaesthetized with urethane and chloralose and vagotomized. Sympathetic postganglionic discharge was recorded from single fibres of the renal nerve. Inhibitory responses were elicited by single shocks or short trains (2-5 shocks at 10 Hz) and assessed from peri-stimulus time histograms. Clear-cut inhibition of the sympathetic discharge was observed in 6 out of 10 fibres. It was evoked by one shock in 5 fibres and by two shocks in 1 fibre. The mean latency of the inhibitory response elicited by one shock was 318 +/- 18 ms and its duration amounted to 196 +/- 22 ms (mean +/- SE). The increase in the number of shocks prolonged the duration of the inhibitory response without markedly affecting their latency.
在兔子身上研究了交感神经放电对主动脉C纤维阈下激活的抑制反应模式。动物用乌拉坦和氯醛糖麻醉并切断迷走神经。从肾神经的单纤维记录交感神经节后放电。通过单次电击或短串刺激（10Hz下2-5次电击）引发抑制反应，并从刺激周围时间直方图进行评估。在10根纤维中有6根观察到交感神经放电的明确抑制。5根纤维由单次电击诱发，1根纤维由两次电击诱发。单次电击诱发的抑制反应的平均潜伏期为318±18毫秒，持续时间为196±22毫秒（平均值±标准误）。电击次数增加延长了抑制反应的持续时间，但对其潜伏期没有明显影响。
