Neubauer S H, Ferris A M, Chase C G, Fanelli J, Thompson C A, Lammi-Keefe C J, Clark R M, Jensen R G, Bendel R B, Green K W
Department of Nutritional Sciences, University of Connecticut, Storrs 06269-4017.
Am J Clin Nutr. 1993 Jul;58(1):54-60. doi: 10.1093/ajcn/58.1.54.
Breast milk lactose, total nitrogen, conductivity, osmolality, and intake by infants of 33 women with insulin-dependent diabetes mellitus (IDDM), 33 control women without diabetes, and 11 reference women were determined in a 3-mo study of lactation. Milk of women with IDDM had significantly lower lactose and higher total nitrogen (2-3 d postpartum), and their infants had significantly less milk intake (7-14 d postpartum) than did control or reference women. Total nitrogen was negatively correlated with milk lactose for women with IDDM at all times and for control women through day 14 postpartum. The data indicate delayed lactogenesis for women with IDDM, which was more likely to occur with poor metabolic control. Differences in milk composition of women with IDDM do not preclude them from breast-feeding their infants.
在一项为期3个月的泌乳研究中，测定了33名胰岛素依赖型糖尿病（IDDM）女性、33名无糖尿病的对照女性和11名参考女性的母乳乳糖、总氮、电导率、渗透压以及婴儿摄入量。IDDM女性的乳汁乳糖含量显著较低，总氮含量较高（产后2 - 3天），且其婴儿的摄入量显著低于对照或参考女性（产后7 - 14天）。在所有时间点，IDDM女性的总氮与乳汁乳糖呈负相关，产后14天内对照女性也是如此。数据表明，IDDM女性的泌乳过程延迟，代谢控制不佳时更易发生。IDDM女性乳汁成分的差异并不妨碍她们母乳喂养婴儿。
