Ott W J
Department of Obstetrics and Gynecology, St. John's Mercy Medical Center, St. Louis, MO 63141-8277.
Am J Obstet Gynecol. 1993 Jun;168(6 Pt 1):1710-5; discussion 1715-7. doi: 10.1016/0002-9378(93)90681-8.
A retrospective study was undertaken to determine if premature infants had a higher incidence of intrauterine growth retardation than term infants did. If premature labor is significantly associated with intrauterine growth retardation, then defining intrauterine growth retardation with a population-specific postnatal birth weight for gestational age curve would underestimate the incidence in preterm infants.
Data for the year 1990 were used to construct a postnatal birth weight for gestational-age curve. This curve was then used to analyze 1991 birth weight data and to determine the incidence of intrauterine growth retardation (< 10th percentile) at each week of gestation. Infants were also classified as having intrauterine growth retardation on the basis of an additional postnatal birth weight for gestational-age curve and two antenatal ultrasonic estimated fetal-weight-for-gestational-age curves.
Analysis of the 1991 delivery data indicated that both ultrasonography curves showed a significant decrease in the incidence of intrauterine growth retardation with advancing gestational age, whereas the postnatal curves did not.
The results give full support to previous reports that suggest intrauterine growth retardation is more common in preterm than in term infants and are consistent with the hypothesis that intrauterine growth retardation is significantly related to premature birth.
进行一项回顾性研究，以确定早产儿宫内生长迟缓的发生率是否高于足月儿。如果早产与宫内生长迟缓显著相关，那么使用针对特定人群的出生体重与胎龄曲线来定义宫内生长迟缓会低估早产儿的发生率。
使用1990年的数据构建出生体重与胎龄曲线。然后用该曲线分析1991年的出生体重数据，并确定妊娠各周宫内生长迟缓（<第10百分位数）的发生率。婴儿还根据另一条出生体重与胎龄曲线以及两条产前超声估计胎儿体重与胎龄曲线被分类为患有宫内生长迟缓。
对1991年分娩数据的分析表明，两条超声曲线均显示随着胎龄增加，宫内生长迟缓的发生率显著下降，而出生后曲线则不然。
研究结果充分支持先前的报告，即宫内生长迟缓在早产儿中比足月儿更常见，并且与宫内生长迟缓与早产显著相关的假设一致。
