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创伤后应激障碍中的短期记忆缺陷。

Deficits in short-term memory in posttraumatic stress disorder.

作者信息

Bremner J D, Scott T M, Delaney R C, Southwick S M, Mason J W, Johnson D R, Innis R B, McCarthy G, Charney D S

机构信息

Department of Psychiatry, Yale University School of Medicine, New Haven, Conn.

出版信息

Am J Psychiatry. 1993 Jul;150(7):1015-9. doi: 10.1176/ajp.150.7.1015.

Abstract

OBJECTIVE

The purpose of this study was to compare the memory function of patients with posttraumatic stress disorder (PTSD) to that of matched comparison subjects.

METHOD

Vietnam veterans with combat-related PTSD (N = 26) were compared to physically healthy comparison subjects (N = 15) matched for age, race, sex, years of education, handedness, socioeconomic status, and alcohol abuse. Memory and intelligence were assessed with a battery of neuropsychological tests, including the Russell revision of the Wechsler Memory Scale, the Selective Reminding Test, and subtests of the Wechsler Adult Intelligence Scale-Revised (WAIS-R).

RESULTS

The PTSD patients scored significantly lower than the comparison subjects on the Wechsler Memory Scale logical memory measures for immediate recall (mean = 11.6, SD = 3.3 versus mean = 20.9, SD = 6.6) and delayed recall (mean = 8.0, SD = 3.3 versus mean = 17.8, SD = 6.4). The PTSD patients also scored significantly lower on the total recall, long-term storage, long-term retrieval, and delayed recall measures for the verbal component of the Selective Reminding Test and on the recall, long-term storage, long-term retrieval, and continuous long-term retrieval measures for the visual component of the Selective Reminding Test. There was no significant difference between the PTSD patients and comparison subjects in prorated full-scale IQ as measured by the WAIS-R.

CONCLUSIONS

Patients with PTSD may have deficits in short-term memory. Counseling and rehabilitation that address these deficits may be of value for PTSD patients.

摘要

目的

本研究旨在比较创伤后应激障碍(PTSD)患者与匹配的对照受试者的记忆功能。

方法

将与战斗相关的创伤后应激障碍的越南退伍军人(N = 26)与年龄、种族、性别、受教育年限、利手、社会经济地位和酒精滥用情况相匹配的身体健康的对照受试者(N = 15)进行比较。通过一系列神经心理学测试评估记忆和智力,包括韦氏记忆量表的拉塞尔修订版、选择性提醒测试以及韦氏成人智力量表修订版(WAIS-R)的子测试。

结果

在韦氏记忆量表的即时回忆逻辑记忆测量(均值 = 11.6,标准差 = 3.3,对比均值 = 20.9,标准差 = 6.6)和延迟回忆(均值 = 8.0,标准差 = 3.3,对比均值 = 17.8,标准差 = 6.4)方面,PTSD患者的得分显著低于对照受试者。在选择性提醒测试的言语部分的总回忆、长期存储、长期检索和延迟回忆测量以及选择性提醒测试的视觉部分的回忆、长期存储、长期检索和连续长期检索测量方面,PTSD患者的得分也显著较低。通过WAIS-R测量的比例全量表智商,PTSD患者与对照受试者之间没有显著差异。

结论

PTSD患者可能存在短期记忆缺陷。针对这些缺陷的咨询和康复对PTSD患者可能有价值。

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