通过体积置换技术快速准确地测量大鼠实体瘤的生长及瘤床变化。
Rapid and accurate measurement of growth of solid tumours and changes in the tumour bed in the rat by the technique of volumetric displacement.
作者信息
Van Den Brenk H A, Stone M G, Burns J W, Crowe M C
出版信息
Br J Cancer. 1977 Jan;35(1):92-9. doi: 10.1038/bjc.1977.8.
An apparatus which has been widely used in rats for measuring swelling of the foot induced locally by inflammatory agents has been adapted to measure rapidly, accurately and objectively, the growth of tumour cells transplanted to the foot, and the reactions of the normal tissues (tumour bed) to tumour growth. General features on the apparatus and the techniques used are described. Examples are provided of preliminary measurements made of normal growth of the foot, reactions of the foot to two injurious agents (histamine and Corynebacterium parvum) and of growth of allogeneic (W256) tumour cells.
一种广泛用于大鼠的测量炎症介质局部诱导足部肿胀的仪器，已被改装用于快速、准确且客观地测量移植到足部的肿瘤细胞的生长情况，以及正常组织（肿瘤床）对肿瘤生长的反应。文中描述了该仪器的总体特征及所采用的技术。还给出了对足部正常生长、足部对两种损伤因子（组胺和短小棒状杆菌）的反应以及同种异体（W256）肿瘤细胞生长进行初步测量的示例。
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