重组人促红细胞生成素在一名耶和华见证会信徒中的应用。

Use of recombinant human erythropoietin in a Jehovah's Witness.

作者信息

Koenig H M, Levine E A, Resnick D J, Meyer W J

机构信息

Department of Anesthesiology, University of Illinois-Chicago College of Medicine 60612.

出版信息

J Clin Anesth. 1993 May-Jun;5(3):244-7. doi: 10.1016/0952-8180(93)90024-9.

DOI:10.1016/0952-8180(93)90024-9

PMID:8318245

Abstract

We report the case of a Jehovah's Witness who bled massively, refused blood transfusion, and survived profound anemia (hematocrit = 5.6%) intact. The patient was treated with recombinant human erythropoietin, parenteral iron, and oxygen. The pharmacology and hematopoietic response to erythropoietin are discussed. We suggest considering this therapy for acutely anemic patients who refuse transfusion to decrease the duration of the most severe anemia.

摘要

我们报告了一例耶和华见证人的病例，该患者大量出血，拒绝输血，却在严重贫血（血细胞比容 = 5.6%）的情况下安然存活。患者接受了重组人促红细胞生成素、胃肠外铁剂和氧气治疗。文中讨论了促红细胞生成素的药理学及造血反应。我们建议对于拒绝输血的急性贫血患者考虑采用这种疗法，以缩短最严重贫血阶段的持续时间。