微血管造影术——一种研究实验性糖尿病肾病的灵敏方法。
Microangiography--a sensitive method for studying experimental diabetic nephropathy.
作者信息
Merikanto J, Hietala S O, Lithner F, Hägg E, Päivänsalo M
机构信息
Department of Diagnostic Radiology, University Hospital, Umeå, Sweden.
出版信息
Acta Radiol. 1993 Jul;34(4):376-80.
Microangiographic and conventional histopathologic investigations of the kidney were compared in 15 alloxan diabetic and 7 nondiabetic control rats. Contrary to the relatively sparse histologic lesions, microangiography disclosed advanced vascular abnormalities, including arteriolar aneurysms, which increased with the duration of diabetes. It is concluded that microangiography is a sensitive and suitable method for studying the development of microvascular lesions of the kidney in experimental diabetes.
对15只四氧嘧啶糖尿病大鼠和7只非糖尿病对照大鼠的肾脏进行了微血管造影和传统组织病理学检查。与相对稀疏的组织学病变相反，微血管造影显示出严重的血管异常，包括小动脉动脉瘤，且其随着糖尿病病程的延长而增加。结论是，微血管造影是研究实验性糖尿病中肾脏微血管病变发展的一种敏感且合适的方法。
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