Niklasson A, Karlberg P
Department of Paediatrics I, University of Göteborg, Sweden.
Acta Paediatr. 1993 Apr;82(4):333-9. doi: 10.1111/j.1651-2227.1993.tb12691.x.
A new methodology for evaluation of weight in relation to length normalized for sex and gestational age (leanness/fatness) in the newborn infant is presented. Using standard deviation scores (SDS) for weight and length in a linear regression model, a new continuous variable called LEANSDS has been constructed with intercept = zero, regression coefficient = 0.7152, SD = 0.6988 and r2 = 0.51, irrespective of gender and gestational age within the range 34-43 weeks' gestation. The model is based on the Swedish 1986 Medical Birth Register and was tested on the 1985 year cohort. The reference material consisted of live-born, singleton infants considered "healthy". This new variable is independent of length. A chart is presented which simplifies visual evaluation. Using -2 SD as the cut-off limit, approximately one-third of light-for-dates infants are also lean, while two-thirds of the lean infants are not light for dates. Proportions of "not healthy" live-born infants and still births are given. Using another method, based on weight and length, and with some approximations needed for calculation of a comparable BW/BLSDS, the correlation was 0.9974, but this calculation is more elaborate and the comparable chart more complex. This method reveals the influence of gestational age on the relationship between weight and length, indicating a "prenatal puberty". Empirically, the logarithmic relationship found between weight and length indicates a ponderal index exponent of 2.4-2.5 instead of 3. LEANSDS, with its continuous nature, also gives the degree of deviation in each individual and in groups of infants, and can be added together and further analysed with improved sensitivity.
本文提出了一种评估新生儿体重与根据性别和胎龄进行标准化的身长(瘦/胖)关系的新方法。在线性回归模型中使用体重和身长的标准差评分(SDS),构建了一个名为LEANSDS的新连续变量,其截距=0,回归系数=0.7152,标准差=0.6988,r2=0.51,无论性别和胎龄在34-43周范围内如何。该模型基于瑞典1986年医学出生登记册,并在1985年队列中进行了测试。参考材料包括被认为“健康”的活产单胎婴儿。这个新变量与身长无关。给出了一个简化视觉评估的图表。以-2个标准差作为截断界限,约三分之一小于胎龄儿也是瘦的,而三分之二的瘦婴儿并非小于胎龄儿。给出了“不健康”活产婴儿和死产的比例。使用另一种基于体重和身长的方法,并且在计算可比的体重/身长标准差评分(BW/BLSDS)时需要一些近似值,相关性为0.9974,但这种计算更复杂,可比图表也更复杂。这种方法揭示了胎龄对体重和身长关系的影响,表明存在“产前青春期”。根据经验,体重和身长之间的对数关系表明 ponderal 指数指数为2.4-2.5而非3。具有连续性质的LEANSDS还给出了每个个体和婴儿组的偏差程度,并且可以相加并以更高的敏感性进行进一步分析。