Morgan J P, Bahr A, Franti C E, Bailey C S
Department of Radiological Sciences, School of Veterinary Medicine, University of California, Davis 95616.
J Am Vet Med Assoc. 1993 Jun 1;202(11):1877-82.
The records of 161 German Shepherd Dogs were divided into groups depending on whether there was a radiographic diagnosis of degenerative disk disease (DDD) involving the lumbosacral disk and lumbosacral transitional vertebral segments (TVS) and whether the dogs had cauda equina syndrome (CES). Statistical analysis of the data suggested an association between TVS and CES and an association between DDD and CES. Establishment of confidence intervals revealed the group without either DDD or TVS indicators differed markedly from the other 3 groups of CES relative to the presence of DDD and TVS. There was some overlap in the confidence intervals, but the proportions of CES were higher when DDD and TVS were both evident. This suggests that the important clinical syndrome of CES is at least partially dependent on TVS, which is probably an inherited condition. Because German Shepherd Dogs have a higher frequency of TVS than dogs of other breeds, this partially explains the higher frequency of CES in this breed. Because TVS are probably familial, we suggest the presence of this lesion should be considered in selection of breeding stock. Although it is believed that DDD is partially dependent on the existence of TVS, it is known that DDD can develop in the absence of TVS.
161只德国牧羊犬的记录根据是否有涉及腰骶椎间盘和腰骶过渡性椎体节段（TVS）的退行性椎间盘疾病（DDD）的影像学诊断以及这些犬是否患有马尾综合征（CES）进行分组。对数据的统计分析表明TVS与CES之间存在关联，DDD与CES之间也存在关联。置信区间的建立显示，没有DDD或TVS指标的组与其他3组CES在DDD和TVS的存在方面有显著差异。置信区间存在一些重叠，但当DDD和TVS都明显时，CES的比例更高。这表明重要的临床综合征CES至少部分取决于TVS，而TVS可能是一种遗传状况。由于德国牧羊犬的TVS发生率高于其他品种的犬，这部分解释了该品种中CES发生率较高的原因。因为TVS可能是家族性的，我们建议在选择种畜时应考虑这种病变的存在。虽然人们认为DDD部分取决于TVS的存在，但已知在没有TVS的情况下DDD也会发生。
