Alisauskaite Neringa, Cizinauskas Sigitas, Jeserevics Janis, Rakauskas Mindaugas, Cherubini Giunio Bruto, Anttila Marjukka, Steffen Frank
Department of Small Animal Surgery, Neurology Service, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Referral Animal Hospital Aisti, Vantaa, Finland.
J Vet Intern Med. 2019 May;33(3):1376-1383. doi: 10.1111/jvim.15470. Epub 2019 Mar 7.
There is a successful outcome after surgical management of spinal arachnoid diverticula (SAD) in up to 82% of cases.
HYPOTHESIS/OBJECTIVES: We hypothesized that Pugs have favorable short-term and poor long-term prognosis after surgical treatment of thoracolumbar SAD. The aim of the present investigation was to describe clinical findings, short- and long-term outcomes, and follow-up magnetic resonance imaging (MRI) findings in Pugs with thoracolumbar SAD.
Twenty-five client owned Pugs with 12-month follow-up information after surgical treatment of thoracolumbar SAD.
Multicenter retrospective case series. All medical records were searched for Pugs diagnosed with SAD. Data regarding signalment, history, surgical procedure, outcome, histopathology, and follow-up MRI results were extracted.
Mean age at presentation was 7.32 (range 2-11) years, 80% were males. Short-term outcome was available in 25 dogs, and improvement was confirmed in 80% of dogs. Long-term outcome was available in 21 dogs, and deterioration was confirmed in 86% of cases, with late-onset recurrence of clinical signs after initial postsurgical improvement affecting 85% of Pugs. A moderate correlation (r = 0.50) was found between duration of clinical signs and outcome. In 8 dogs with deteriorating clinical signs, follow-up MRI revealed regrowth of the SAD in 2 cases, new SAD formation in 2 cases, and intramedullary T2W hyperintensity/syringomyelia in 6 cases.
This study suggests that Pugs with thoracolumbar SAD do not have a favorable long-term prognosis after surgical treatment for reasons yet to be determined.
脊柱蛛网膜憩室（SAD）手术治疗后高达82%的病例有成功的结果。
假设/目的：我们假设巴哥犬胸腰椎SAD手术治疗后短期预后良好但长期预后不佳。本研究的目的是描述胸腰椎SAD巴哥犬的临床发现、短期和长期结果以及随访磁共振成像（MRI）结果。
25只客户拥有的巴哥犬，在胸腰椎SAD手术治疗后有12个月的随访信息。
多中心回顾性病例系列。检索所有医疗记录以查找诊断为SAD的巴哥犬。提取有关信号、病史、手术过程、结果、组织病理学和随访MRI结果的数据。
就诊时的平均年龄为7.32岁（范围2 - 11岁），80%为雄性。25只犬有短期结果，80%的犬得到改善。21只犬有长期结果，86%的病例病情恶化，85%的巴哥犬在术后初期改善后出现临床症状的迟发性复发。临床症状持续时间与结果之间存在中度相关性（r = 0.50）。在8只临床症状恶化的犬中，随访MRI显示2例SAD再生长，2例新SAD形成，6例脊髓内T2加权高信号/脊髓空洞症。
本研究表明，胸腰椎SAD的巴哥犬手术治疗后长期预后不佳，原因尚待确定。
