Otaka K, Enzan K, Matsumoto J, Nagata H, Matsuura S, Suzuki M
Department of Anesthesiology, Akita University School of Medicine.
Masui. 1993 Jun;42(6):926-30.
We report an anesthetic management for Cesarean section and clipping of aneurysm in a pregnant woman with a subarachnoidal hemorrhage secondary to a ruptured cerebral aneurysm. Anesthesia was induced with thiopental, vecuronium and sevoflurane, and maintained with sevoflurane (0.5-1%) before the delivery. Apgar score at 1 min was 1, but after 30 min her activity became almost normal. After the delivery, anesthesia was maintained with fentanyl for clipping surgery, because sevoflurane may inhibit uterine contraction and increase bleeding from the uterus after the delivery. We also infused prostaglandin E1 continuously at a rate of 50-70 ng.kg-1.min-1 to control arterial blood pressure and to maintain good contraction of the uterus during clipping surgery. We conclude that prostaglandin E1 is useful as a vasodilator after delivery because prostaglandin E1 contracts the uterus.
我们报告了一例针对蛛网膜下腔出血继发于破裂脑动脉瘤的孕妇进行剖宫产及动脉瘤夹闭术的麻醉管理。麻醉诱导采用硫喷妥钠、维库溴铵和七氟醚,分娩前用七氟醚(0.5 - 1%)维持麻醉。1分钟时阿氏评分1分,但30分钟后其活动几乎恢复正常。分娩后,由于七氟醚可能抑制子宫收缩并增加产后子宫出血,因此用芬太尼维持麻醉进行夹闭手术。我们还以50 - 70 ng·kg⁻¹·min⁻¹的速率持续输注前列腺素E1,以控制动脉血压并在夹闭手术期间维持子宫良好收缩。我们得出结论,前列腺素E1在产后作为血管扩张剂是有用的,因为前列腺素E1可使子宫收缩。