一种使用微丝和可植入微操纵器记录清醒、不受约束的猫脑干神经元活动的技术。
A technique for recording the activity of brain-stem neurones in awake, unrestrained cats using microwires and an implantable micromanipulator.
作者信息
Banks D, Kuriakose M, Matthews B
机构信息
Department of Physiology, School of Medical Sciences, University of Bristol, UK.
出版信息
J Neurosci Methods. 1993 Jan;46(1):83-8. doi: 10.1016/0165-0270(93)90144-g.
A new technique is described which is suitable for long-term recording of the activity of neurones in the brain of an awake, unrestrained cat. By using telescopic electrodes, neurones up to 39 mm from the cranial surface can be reached with a miniature micromanipulator which is small enough to be left in place between recording sessions. The most stable recordings have been obtained with electrodes made from microwire, with which units have been held for up to 8 h.
本文描述了一种新技术，适用于对清醒、不受束缚的猫脑神经元活动进行长期记录。通过使用伸缩式电极，用一个小型微操纵器就能接触到距颅表面达39毫米的神经元，该微操纵器体积小，记录间隙时可留在原位。使用微丝制成的电极获得了最稳定的记录，用这种电极记录单个神经元可达8小时。
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