Ruiter D J, Byck W, Pauwels E K, Taconis W K, Spaander P J
Cancer. 1977 Jan;39(1):172-7. doi: 10.1002/1097-0142(197701)39:1<172::aid-cncr2820390128>3.0.co;2-v.
The accuracy of scintigraphy in focal liver disease was evaluated by comparing the scintigraphic and autopsy findings in 59 patients. The interval between scintigraphy and autopsy was not more than a few weeks. The overall agreement rate was 49 in 59 (83%), with four out of 26 (15%) false positive and six out of 33 (18%) false negative reports. Defects smaller than 2 1/2 cm were the principal source of false negative reports. The accuracy of interpretation in cases with liver weights up to 2000 g was significantly (P less than 0.025) lower than for higher weights. Detection of a single focal lesion by scintigraphy was found to be unreliable (only two out of 13 correct). Estimation of spleen weights by scintigraphy was disappointing. Liver weight estimates were somewhat more satisfactory.
通过比较59例患者的闪烁扫描结果与尸检结果，评估了闪烁扫描在局灶性肝病中的准确性。闪烁扫描与尸检之间的间隔不超过几周。总体符合率为59例中的49例（83%），26例中有4例（15%）假阳性报告，33例中有6例（18%）假阴性报告。小于2.5厘米的缺损是假阴性报告的主要来源。肝脏重量达2000克的病例中，解读的准确性显著低于（P<0.025）更高重量的病例。发现通过闪烁扫描检测单个局灶性病变不可靠（13例中仅2例正确）。通过闪烁扫描估计脾脏重量令人失望。肝脏重量估计则稍令人满意。
