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[犬新孢子虫作为幼犬跛行症状的一个病因]

[Neospora caninum as a cause of lameness symptoms in young dogs].

作者信息

Wouda W, de Jong J K, van Knapen F, Walvoort H C

机构信息

Gezondheidsdienst voor Dieren Noord-Nederland, Drachten.

出版信息

Tijdschr Diergeneeskd. 1993 Jun 15;118(12):397-401.

PMID:8322363
Abstract

At the age of three weeks, two Labrador retriever puppies, out of a litter of nine, suffered from diarrhoea and muscular weakness. One puppy died within two days. The other was killed after a tetraparalysis had developed. Two weeks later a third puppy was killed because of a paretic hind leg. At the age of five months another dog had to be euthanized because of progressive hind limb ataxia. Pathological examination revealed polyradiculoneuritis, multifocal encephalomyelitis and polymyositis. In the lesions, particularly in the nerve roots, free and clustered protozoal tachyzoites were found. In the central nervous system tissue cysts were seen. By use of immunohistochemistry the protozoal organisms were identified as Neospora caninum, a newly recognized protozoan in the dog. Fresh bovine heart, that had been fed to the puppies, is regarded as the possible source of infection.

摘要

一窝九只拉布拉多寻回犬幼犬在三周龄时,有两只出现腹泻和肌肉无力症状。其中一只幼犬在两天内死亡。另一只在发展为四肢瘫痪后被处死。两周后,第三只幼犬因后腿麻痹被处死。五个月龄时,另一只犬因进行性后肢共济失调不得不实施安乐死。病理检查显示多神经根神经炎、多灶性脑脊髓炎和多发性肌炎。在病变部位,特别是神经根处,发现了游离的和成群的原虫速殖子。在中枢神经系统组织中可见组织囊肿。通过免疫组织化学方法,将这些原虫鉴定为犬新孢子虫,这是一种在犬类中新发现的原生动物。曾喂食给幼犬的新鲜牛心被认为是可能的感染源。

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