Graham S G, Aitkenhead A R
University Department of Anaesthesia, Queen's Medical Centre, Nottingham.
Anaesthesia. 1993 Jun;48(6):471-5. doi: 10.1111/j.1365-2044.1993.tb07064.x.
Fifty-seven healthy female patients who underwent gynaecological laparoscopic surgery received either desflurane or propofol for induction and maintenance of anaesthesia. Inhalational induction was generally well tolerated, and consciousness was lost in approximately 2 min (mean end-tidal concentrations of desflurane were 8.3% with 60% nitrous oxide, and 7.1% with oxygen). Recovery of consciousness and orientation were more rapid in patients in whom anaesthesia was maintained with desflurane than with propofol, but there were no differences in psychomotor function test scores at 30 min. The data suggest that desflurane provides controllable anaesthesia and rapid recovery of consciousness after laparoscopic surgery.
57名接受妇科腹腔镜手术的健康女性患者在麻醉诱导和维持过程中分别使用了地氟烷或丙泊酚。吸入诱导通常耐受性良好,意识在大约2分钟内消失(使用60%氧化亚氮时地氟烷的平均呼气末浓度为8.3%,使用氧气时为7.1%)。与使用丙泊酚维持麻醉的患者相比,使用地氟烷维持麻醉的患者意识和定向力恢复更快,但30分钟时的精神运动功能测试得分没有差异。数据表明,地氟烷可提供可控的麻醉效果,并使腹腔镜手术后意识快速恢复。