Zeller J, Bougnères P F
Service de Pédiatrie, Hôpital Saint-Vincent de Paul, PARIS.
Ann Pediatr (Paris). 1993 Apr;40(4):276-80.
Epidemiological data on diarrhea due to Rotavirus are similar enough across different regions of the world to allow the pooling of clinical studies of Actapulgite for the treatment of acute diarrhea in infants and children in France and Africa. A total of 7,616 infants and children were entered into these open or placebo-controlled trials. Most patients were under two years of age, results of the analysis confirmed the antidiarrheal efficacy and safety of Actapulgite.
轮状病毒引起的腹泻的流行病学数据在世界不同地区足够相似,从而可以汇总法国和非洲关于凹凸棒石治疗婴幼儿急性腹泻的临床研究。共有7616名婴幼儿参与了这些开放或安慰剂对照试验。大多数患者年龄在两岁以下,分析结果证实了凹凸棒石的止泻疗效和安全性。