Stehling M K, Schmitt F, Ladebeck R
Department of Neurosurgery, University of Erlangen, Germany.
J Magn Reson Imaging. 1993 May-Jun;3(3):471-4. doi: 10.1002/jmri.1880030307.
Echo-planar magnetic resonance (MR) imaging was used to observe signal intensity changes in the human brain during hypoxia. Increasing arterial blood levels of deoxyhemoglobin (0%-42%) during prolonged apnea were monitored with a pulse oximeter and correlated with gray matter and white matter signal attenuation of 13% and 20%, respectively. The results suggest the possibility of using deoxyhemoglobin boluses as a physiologic, intravascular susceptibility contrast agent for assessment of local cerebral oxygen utilization.
回波平面磁共振成像用于观察人类大脑在缺氧过程中的信号强度变化。使用脉搏血氧仪监测长时间呼吸暂停期间动脉血中脱氧血红蛋白水平的升高（0% - 42%），并将其与灰质和白质信号衰减分别为13%和20%相关联。结果表明，使用脱氧血红蛋白团注作为一种生理性血管内磁化率对比剂来评估局部脑氧利用率具有可能性。
