Fraulin F O, Thurston O G
Department of Surgery, University of Alberta, Edmonton.
Can J Surg. 1993 Jun;36(3):261-5.
Tissue cultures from perforations of the lower intestinal tract commonly yield both aerobes (coliform organisms) and anaerobes (Bacteroides sp. and Clostridium sp.). To determine the consistency of this pattern and the value of intraoperative cultures, the authors reviewed the hospital records of 115 patients with perforation of the appendix (100 patients) or colon (15 patients), treated between 1987 and 1990, in whom organisms were cultured from tissue samples taken intraoperatively. Attention was paid to the organisms cultured, their distribution and antibiotic sensitivity in initial samples and in subsequent samples obtained when there were septic complications. On average, 4.7 bacterial isolates per patient were obtained. The common organisms were as expected: Bacteroides fragilis, Escherichia coli and Clostridium sp. Although the culture results did not affect the management of these patients, the sensitivity of Bacteroides fragilis to cefoxitin was found to be lower than expected, indicating a shift in sensitivity.
下肠道穿孔的组织培养通常会培养出需氧菌（大肠菌属微生物）和厌氧菌（拟杆菌属和梭菌属）。为了确定这种模式的一致性以及术中培养的价值，作者回顾了1987年至1990年间接受治疗的115例阑尾穿孔（100例）或结肠穿孔（15例）患者的医院记录，这些患者术中采集的组织样本进行了微生物培养。研究关注了培养出的微生物、它们在初始样本以及出现败血症并发症时获取的后续样本中的分布和抗生素敏感性。平均每位患者获得4.7株细菌分离株。常见的微生物正如预期：脆弱拟杆菌、大肠杆菌和梭菌属。尽管培养结果并未影响这些患者的治疗，但发现脆弱拟杆菌对头孢西丁的敏感性低于预期，表明敏感性发生了变化。
