Palayew M, Briedis D, Libman M, Michel R P, Levy R D
Division of Respiratory Medicine, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada.
Chest. 1993 Jul;104(1):307-9. doi: 10.1378/chest.104.1.307.
A 57-year-old man undergoing intravesical immunotherapy with BCG for transitional cell bladder carcinoma presented with dyspnea, fever, hypoxemia, and a diffuse micronodular pattern on chest radiograph. Transbronchial biopsy specimen revealed widespread noncaseating granulomas, and acid-fast bacilli were identified in sputum as well as in the biopsy tissue. The patient's condition responded promptly to antituberculous antibiotics given in conjunction with corticosteroids. Although no growth was evident on TB culture of the specimens, the presence of organisms indicates a probable infectious cause of the pulmonary disease process.
一名57岁接受卡介苗膀胱内免疫疗法治疗移行细胞膀胱癌的男性患者，出现呼吸困难、发热、低氧血症，胸部X线片显示弥漫性微结节影。经支气管活检标本显示广泛的非干酪样肉芽肿，痰液及活检组织中均发现抗酸杆菌。患者的病情在给予抗结核抗生素联合皮质类固醇后迅速缓解。尽管标本的结核培养未见明显生长，但病原体的存在提示肺部疾病过程可能由感染引起。
