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膀胱内灌注卡介苗后发生的肉芽肿性肺炎。需要何种治疗？

Granulomatous pneumonitis following intravesical BCG. What therapy is needed?

作者信息

LeMense G P, Strange C

机构信息

Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston.

出版信息

Chest. 1994 Nov;106(5):1624-6. doi: 10.1378/chest.106.5.1624.

DOI:10.1378/chest.106.5.1624
PMID:7956439
Abstract

A 68-year-old man developed fever, cough, and dyspnea after intravesical bacillus Calmette-Guerin (BCG). Chest radiograph revealed diffuse reticulonodular infiltrates with caseating granulomas on transbronchial biopsy specimen. Cultures were negative and the patient's condition improved with corticosteroids. The mechanism for BCG-induced granulomatous inflammation is poorly understood. Optimal therapy includes corticosteroids.

摘要

一名68岁男性在膀胱内灌注卡介苗（BCG）后出现发热、咳嗽和呼吸困难。胸部X线片显示弥漫性网状结节浸润，经支气管活检标本可见干酪样肉芽肿。培养结果为阴性，患者使用皮质类固醇后病情改善。卡介苗诱导肉芽肿性炎症的机制尚不清楚。最佳治疗方法包括使用皮质类固醇。

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