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[包头市先天性出生缺陷危险因素的条件logistic回归分析]

[Conditional logistic regression analysis of risk factors on congenital birth defects in Baotou].

作者信息

Zhang J Q

机构信息

Department of Epidemiology in Baotou Medical College.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 1993 Jan;27(1):29-31.

PMID:8325175
Abstract

Congenital defects are one of the common diseases in the newborns, and are important factors affecting the quality of the population. This survey was done to find risk factors related to congenital defects and to provide scientific basis for promoting birth quality. In this paper, a case-control study on 90 cases using 1:2 matching was carried out in Baotou area, and conditional logistic regression analysis showed that the following six major risk factors were associated with birth defects, i.e.: intake of certain drugs during pregnancy, exposure to radioactive rays, and contacting certain harmful chemical substances, common cold and fever during the period of pregnancy, smoking addiction of baby's father and the family history of certain defects of baby's parents.

摘要

先天性缺陷是新生儿常见疾病之一,是影响人口素质的重要因素。本次调查旨在找出与先天性缺陷相关的危险因素,为提高出生质量提供科学依据。本文在包头地区对90例病例采用1:2匹配进行病例对照研究,条件logistic回归分析显示,以下六个主要危险因素与出生缺陷有关,即:孕期服用某些药物、接触放射性射线、接触某些有害化学物质、孕期患感冒发烧、婴儿父亲吸烟成瘾以及婴儿父母某些缺陷的家族史。

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