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心肌梗死后心脏死亡率的长期降低:一项综合康复计划的10年结果

Long-term reduction of cardiac mortality after myocardial infarction: 10-year results of a comprehensive rehabilitation programme.

作者信息

Hedbäck B, Perk J, Wodlin P

机构信息

Department of Internal Medicine, Oskarshamn District Hospital, Sweden.

出版信息

Eur Heart J. 1993 Jun;14(6):831-5. doi: 10.1093/eurheartj/14.6.831.

Abstract

The long-term outcome of different methods of post-MI care has been studied in two non-selected groups of MI patients: an intervention group (n = 147), participating in a cardiac rehabilitation (CR) programme, was compared to a reference group receiving standard care (n = 158). The CR programme included a post-MI clinic, physical training, information on smoking and diet, and psychological support. After 5 years there was no difference in mortality (29.3 vs 31.6%), but the recurrence rate of non-fatal MI (17.3 vs 33.3%, P < 0.05) and of total cardiac events (39.5 vs 53.2%, P < 0.05) was lower in the intervention group, and more patients were still at work (51.8 vs 27.4% P < 0.01). After 10 years there was a reduction in total (42.2 vs 57.6% P < 0.01) and cardiac mortality (36.7 vs 48.1% P < 0.001). Fewer patients in the intervention group suffered from non-fatal reinfarction (28.6 vs 39.9%, P < 0.001). Among those patients who had not yet reached the age of retirement more patients had resumed employment (58.6 vs 22.0% P < 0.05). We conclude, that the secondary preventive effect of the programme has contributed to the higher rate of survival.

摘要

在两组未经挑选的心肌梗死(MI)患者中研究了不同心肌梗死后护理方法的长期结果:干预组(n = 147)参加心脏康复(CR)计划,并与接受标准护理的参照组(n = 158)进行比较。CR计划包括心肌梗死后门诊、体育锻炼、吸烟和饮食信息以及心理支持。5年后,两组死亡率无差异(29.3%对31.6%),但干预组非致命性心肌梗死的复发率(17.3%对33.3%,P<0.05)和总心脏事件的复发率(39.5%对53.2%,P<0.05)较低,且仍在工作的患者更多(51.8%对27.4%,P<0.01)。10年后,总死亡率(42.2%对57.6%,P<0.01)和心脏死亡率(36.7%对48.1%,P<0.001)有所降低。干预组发生非致命性再梗死的患者较少(28.6%对39.9%,P<0.001)。在尚未达到退休年龄的患者中,恢复工作的患者更多(58.6%对22.0%,P<0.05)。我们得出结论,该计划的二级预防作用有助于提高生存率。

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