锡兰天料木的植物化学研究。

A phytochemical investigation of Homalium ceylanicum.

作者信息

Ekabo O A, Farnsworth N R, Santisuk T, Reutrakul V

机构信息

Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois, Chicago 60612.

出版信息

J Nat Prod. 1993 May;56(5):699-707. doi: 10.1021/np50095a006.

DOI:10.1021/np50095a006

PMID:8326319

Abstract

Vacciniin [4] (6-O-benzoyl-D-glucopyranoside) and two new benzenoid glucosides, homaloside A [1] (1''-O-benzyl-3''-O-benzoyl-alpha-L-arabinopyranosyl(1'''-->4'')- beta-D-glucopyranoside) and homaloside D [2] [1-(1'-hydroxy-6'-oxocyclohex-2'-ene-carboxymethyl)- 5-hydroxyphenyl-6''-O-benzoyl-beta-D-glucopyranoside], were isolated from the n-BuOH fraction of Homalium ceylanicum (Flacourtiaceae). A novel cyclohexenone carboxylic acid ester, 1-hydroxy-6-oxocyclohex-2-enoic acid methyl ester [3], was also isolated from this fraction. The structures were elucidated by chemical and nmr (COLOC, FLOCK, and selective INEPT) techniques.

摘要

从锡兰天料木（大风子科）的正丁醇部分分离得到了vacciniin [4]（6-O-苯甲酰基-D-吡喃葡萄糖苷）以及两种新的苯类糖苷，即homaloside A [1]（1''-O-苄基-3''-O-苯甲酰基-α-L-阿拉伯吡喃糖基(1'''→4'')-β-D-吡喃葡萄糖苷）和homaloside D [2] [1-(1'-羟基-6'-氧代环己-2'-烯-羧甲基)-5-羟基苯基-6''-O-苯甲酰基-β-D-吡喃葡萄糖苷]。还从该部分分离得到了一种新型环己烯酮羧酸酯，1-羟基-6-氧代环己-2-烯酸甲酯[3]。通过化学和核磁共振（COLOC、FLOCK和选择性INEPT）技术阐明了其结构。