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一种使用BGO块状探测器的旋转式正电子发射断层扫描仪:设计、性能与应用

A rotating PET scanner using BGO block detectors: design, performance and applications.

作者信息

Townsend D W, Wensveen M, Byars L G, Geissbuhler A, Tochon-Danguy H J, Christin A, Defrise M, Bailey D L, Grootoonk S, Donath A

机构信息

Division of Nuclear Medicine, University Hospital, Geneva, Switzerland.

出版信息

J Nucl Med. 1993 Aug;34(8):1367-76.

PMID:8326401
Abstract

Recent advances in fully three-dimensional reconstruction for multi-ring PET scanners have led us to explore the potential of a prototype scanner based on the rotation of two opposing arrays of BGO block detectors. The prototype contains only one-third of the number of detectors in the equivalent full ring scanner, resulting in reduced cost. With a lower energy threshold at 250 keV, the absolute efficiency of the scanner is 0.5% and the scatter fraction is 35% for a 20-cm cylinder. Transaxial and axial spatial resolution is about 6 mm. The maximum noise equivalent count rate estimated for a 15-cm diameter cylinder is 36,000 cps at a concentration of 26 kBq/ml. The minimum scan time for a 18F-fluoro-2-deoxyglucose (FDG) brain study is 55 sec. The camera has been validated for clinical applications using both FDG and 82Rb.

摘要

多环正电子发射断层扫描仪(PET)全三维重建技术的最新进展,促使我们探索一种基于两组相对的BGO块状探测器阵列旋转的原型扫描仪的潜力。该原型扫描仪的探测器数量仅为同等全环扫描仪的三分之一,从而降低了成本。在能量阈值为250keV时,对于一个20厘米的圆柱体,该扫描仪的绝对效率为0.5%,散射分数为35%。横向和轴向空间分辨率约为6毫米。对于一个直径15厘米的圆柱体,在浓度为26 kBq/ml时,估计的最大噪声等效计数率为36,000 cps。进行一次18F-氟代脱氧葡萄糖(FDG)脑部检查的最短扫描时间为55秒。该相机已通过使用FDG和82Rb进行临床应用验证。

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