Giugliano L G, Meyer C J, Arantes L C, Ribeiro S T, Giugliano R
Department of Cellular Biology, University of Brasilia.
J Trop Pediatr. 1993 Jun;39(3):183-7. doi: 10.1093/tropej/39.3.183.
Haemolysin production (Hly) and mannose-resistant haemagglutination induction (MRHA) of human (H), bovine (B), and both (HB) erythrocytes was investigated in strains of E. coli isolated from 142 cases of children with diarrhoea aged 0-36 months. Haemolysin production was more frequent in strains isolated from children under 1 year and this characteristic was strongly associated with HB+ haemagglutination (P < 0.005). Isolation frequency of MRHA strains was compared in 53 breastfed and 50 non-breastfed children under 1 year of age. HB+ strains were significantly more frequent in non-breastfed infants (P < 0.025). Severity of diarrhoea evaluated by the number of watery stools per day, was significantly reduced in the breastfed group (P < 0.05). The results suggests that breastfeeding may protect infants against the establishment of HB+ strains which might be acting either as a main pathogen or as an opportunistic strain.
对从142例0至36个月腹泻儿童中分离出的大肠杆菌菌株，研究了其对人（H）、牛（B）及两者（HB）红细胞的溶血素产生（Hly）和耐甘露糖血凝诱导（MRHA）情况。1岁以下儿童分离出的菌株中溶血素产生更为常见，且这一特征与HB +血凝密切相关（P < 0.005）。比较了53名母乳喂养和50名非母乳喂养的1岁以下儿童中MRHA菌株的分离频率。非母乳喂养婴儿中HB +菌株明显更为常见（P < 0.025）。通过每日水样便数量评估的腹泻严重程度，母乳喂养组显著降低（P < 0.05）。结果表明，母乳喂养可能保护婴儿免受HB +菌株的侵袭，这些菌株可能作为主要病原体或机会性菌株起作用。
