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前列腺癌盆腔淋巴结清扫分期:腹腔镜与开放手术技术的比较

Staging pelvic lymphadenectomy for prostate cancer: a comparison of laparoscopic and open techniques.

作者信息

Kerbl K, Clayman R V, Petros J A, Chandhoke P S, Gill I S

机构信息

Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.

出版信息

J Urol. 1993 Aug;150(2 Pt 1):396-8; discussion 399. doi: 10.1016/s0022-5347(17)35491-5.

Abstract

The operative morbidity and convalescence of our initial 30 patients who underwent laparoscopic pelvic lymph node dissections were compared to those of 16 patients who underwent open surgical pelvic lymph node dissections performed at our institution for staging purposes between 1990 and 1992. The average time for laparoscopic pelvic lymph node dissection (199.4 minutes) was nearly twice that of surgical pelvic lymph node dissection (102.4 minutes). However, the blood loss in the former group was significantly less. Oral intake occurred after a mean of 0.63 days in the laparoscopic pelvic lymph node dissection group compared to 2.87 days in the surgical group. Also, laparoscopic pelvic lymph node dissection was superior to surgical pelvic lymph node dissection in terms of average postoperative analgesic use (1.55 versus 47 mg. morphine sulfate), average hospital stay (1.7 versus 5.37 days), average return to normal daily activities (4.94 versus 42.9 days) and interval to full recovery (10.8 versus 65.5 days). However, the incidence of significant complications in the laparoscopic pelvic lymph node dissection group was 13%, with no complications seen in the surgical group. Interestingly, all significant problems in the bilateral laparoscopic pelvic lymph node dissection patients were confined to our initial 12 patients, indicating the steepness of the laparoscopic learning curve.

摘要

我们将1990年至1992年间在本院接受腹腔镜盆腔淋巴结清扫术的最初30例患者的手术发病率和康复情况,与16例为分期目的而接受开放性手术盆腔淋巴结清扫术的患者进行了比较。腹腔镜盆腔淋巴结清扫术的平均时间(199.4分钟)几乎是手术盆腔淋巴结清扫术(102.4分钟)的两倍。然而,前一组的失血量明显较少。腹腔镜盆腔淋巴结清扫术组平均0.63天后开始经口进食,而手术组为2.87天。此外,在平均术后镇痛药物使用量(1.55对47毫克硫酸吗啡)、平均住院时间(1.7对5.37天)、平均恢复正常日常活动时间(4.94对42.9天)以及完全康复间隔时间(10.8对65.5天)方面,腹腔镜盆腔淋巴结清扫术均优于手术盆腔淋巴结清扫术。然而,腹腔镜盆腔淋巴结清扫术组的严重并发症发生率为13%,而手术组未出现并发症。有趣的是,双侧腹腔镜盆腔淋巴结清扫术患者中的所有严重问题都局限于最初的12例患者,这表明腹腔镜技术学习曲线较陡。

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