Geirsson G
Department of Surgery, Sahlgrenska University Hospital, Göteborg, Sweden.
J Urol. 1993 Aug;150(2 Pt 1):427-30. doi: 10.1016/s0022-5347(17)35501-5.
The effect of menthol on the human bladder cooling reflex was studied prospectively in a group of patients with a positive ice water test. Menthol has a selective potentiating action on cutaneous cold receptors and shifts the temperature response curve of the bladder cooling reflex towards higher temperatures in animal experiments. The substance had an almost identical effect on the human bladder, that is it caused a shift of the threshold temperature of the bladder cooling reflex towards a higher value in all tested patients. Thus, it can be concluded that the human bladder cooling reflex originates from cold receptors within the bladder wall.
在一组冰水试验呈阳性的患者中，对薄荷醇对人体膀胱冷觉反射的影响进行了前瞻性研究。在动物实验中，薄荷醇对皮肤冷感受器具有选择性增强作用，并使膀胱冷觉反射的温度反应曲线向更高温度偏移。该物质对人体膀胱产生了几乎相同的影响，即在所有受试患者中，它使膀胱冷觉反射的阈值温度向更高值偏移。因此，可以得出结论，人体膀胱冷觉反射起源于膀胱壁内的冷感受器。
