Uozumi T, Nakano S, Matsunaga K, Tsuji S, Murai Y
Department of Neurology, University of Occupational and Environmental Health, School of Medicine, Fukuoka, Japan.
Neurology. 1993 Jul;43(7):1397-400. doi: 10.1212/wnl.43.7.1397.
We studied the sudomotor potential in the palm of the hand, evoked by magnetic stimulation of the neck, in 15 normal subjects and five patients with dysautonomia. The potentials consisted of two positive peaks (S1, S2), with mean (+/- SD) onset latencies of 408.5 +/- 31.8 and 619 +/- 61.4 msec. The sudomotor potential was clearly obtained only from the palm and was influenced by stimulus intensity, coil position, current direction in the coil, atropine or pilocarpine iontophoresis, and motor effort. With this method, we estimated the postganglionic sympathetic conduction time and the central reflex time, the mean values (+/- SD) of which were 408.5 +/- 31.8 and 323.3 +/- 45.2 msec. In three patients with severe dry skin, the sudomotor potential and the sympathetic skin response were not obtained. A patient with OPCA had a prolonged central reflex time, and a patient with alcoholic polyneuropathy showed a delayed sudomotor potential. Sudomotor potential is a noninvasive and useful method for evaluating sympathetic sudomotor function in patients with central and peripheral nervous system disorders.
我们对15名正常受试者和5名自主神经功能障碍患者进行了研究，通过磁刺激颈部诱发手掌中的汗腺运动电位。这些电位由两个正峰（S1、S2）组成，平均（±标准差）起始潜伏期分别为408.5±31.8毫秒和619±61.4毫秒。汗腺运动电位仅在手掌清晰获得，并受刺激强度、线圈位置、线圈中的电流方向、阿托品或毛果芸香碱离子导入以及运动努力的影响。通过这种方法，我们估计了节后交感神经传导时间和中枢反射时间，其平均值（±标准差）分别为408.5±31.8毫秒和323.3±45.2毫秒。在3名严重皮肤干燥的患者中，未获得汗腺运动电位和交感皮肤反应。一名橄榄桥脑小脑萎缩（OPCA）患者的中枢反射时间延长，一名酒精性多发性神经病患者的汗腺运动电位延迟。汗腺运动电位是评估中枢和周围神经系统疾病患者交感汗腺运动功能的一种非侵入性且有用的方法。
