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单侧睾丸切除术对豚鼠睾丸的代谢影响。

Metabolic effects of unilateral orchiectomy on the guinea pig testis.

作者信息

Noller D W, Howards S S, Panko W

出版信息

Fertil Steril. 1977 Feb;28(2):186-90.

PMID:832731
Abstract

Six months after unilateral orchiectomy, there was a significant increase in the RNA and DNA content of contralateral testes as compared with the testes of age-matched normal guinea pigs. The ratio of RNA to DNA was not affected by orchiectomy, suggesting that the compensatory growth was secondary to hyperplasia rather than hypertrophy. Tritiated thymidine uptake by the contralateral testis was elevated at 2 weeks and 2,4 and 6 months after orchiectomy, confirming that increased metabolic activity occurred in the remaining testis after hemicastration.

摘要

单侧睾丸切除术后六个月,与年龄匹配的正常豚鼠的睾丸相比,对侧睾丸的RNA和DNA含量显著增加。RNA与DNA的比例不受睾丸切除术的影响,这表明代偿性生长是增生而非肥大的结果。在睾丸切除术后2周、2个月、4个月和6个月时,对侧睾丸的氚标记胸腺嘧啶摄取量升高,证实了半侧睾丸切除术后剩余睾丸的代谢活性增加。

相似文献

1
Metabolic effects of unilateral orchiectomy on the guinea pig testis.单侧睾丸切除术对豚鼠睾丸的代谢影响。
Fertil Steril. 1977 Feb;28(2):186-90.
2
[Tissue culture studies on compensatory testicular hypertrophy of the young rabbit after hemicastration].[幼兔半侧睾丸切除术后代偿性睾丸肥大的组织培养研究]
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Pattern of compensatory hypertrophy in contralateral testis after unilateral orchiectomy in immature rabbits.未成熟兔单侧睾丸切除术后对侧睾丸的代偿性肥大模式
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Mechanisms for the testicular hypertrophy which follows hemicastration.半侧睾丸切除术后睾丸肥大的机制。
Endocrinology. 1978 Jan;102(1):16-23. doi: 10.1210/endo-102-1-16.
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Morphometric studies of compensatory testicular hypertrophy in the rat after hemicastration.大鼠半侧睾丸切除术后代偿性睾丸肥大的形态测量学研究。
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Quantitative studies of compensatory testicular hypertrophy following unilateral castration in the boar.公猪单侧去势后睾丸代偿性肥大的定量研究。
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Dynamics of the follicle-stimulating hormone (FSH)-inhibin B feedback loop and its role in regulating spermatogenesis in the adult male rhesus monkey (Macaca mulatta) as revealed by unilateral orchidectomy.单侧睾丸切除揭示成年雄性恒河猴(猕猴)卵泡刺激素(FSH)-抑制素B反馈回路的动态变化及其在调节精子发生中的作用
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引用本文的文献

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The Effect of a Unilateral Orchiectomy before Gonadotoxic Treatment on the Contralateral Testis in Adult and Prepubertal Rats.性腺毒性治疗前单侧睾丸切除术对成年和青春期前大鼠对侧睾丸的影响。
PLoS One. 2016 Oct 21;11(10):e0164922. doi: 10.1371/journal.pone.0164922. eCollection 2016.