Pedersen D E, Overgaard J, Søgaard H, Elbrønd O, Overgaard M
Onkologisk afdeling, Arhus Kommunehospital.
Ugeskr Laeger. 1993 Jul 19;155(29):2255-9.
The UICC 1987 TNM classification system was used to retrospectively analyze the treatment results and prognostic factors in 110 consecutive patients diagnosed and treated from 1970 to 1986. Treatment consisted of surgery, radiotherapy, or a combination. Malignant mixed tumours were seen in 28% of the patients, mucoepidermoid tumours in 18%, adenoid cystic tumours in 15%, acinic tumours in 13%, undifferentiated tumours in 11%, adenocarcinomas in 10%, and other types in 5%. Ten-year corrected survival was 52%, and significant differences in survival were found between: 1. patients with disease stage I-IV (I: 85%, II: 69%, III: 43%, IV: 14%); 2. those with local tumour extension (34%) and without local tumour extension (79%); 3. patients with facial nerve palsy (0%) and without facial nerve palsy (57%); 4. those with low- or intermediate-grade tumours (69% combined) and those with high-grade malignant tumours (30%). Forty-five percent of the patients were cured after primary treatment, as were an additional 22% of those treated for local or neck node recurrences. It is concluded that there is a good correlation between TNM classification of UICC 1987 (stage and local extension of tumour) and prognosis, and that facial nerve palsy and grade of malignancy are important prognostic factors.
采用国际抗癌联盟（UICC）1987年的TNM分类系统，对1970年至1986年间连续诊断和治疗的110例患者的治疗结果及预后因素进行回顾性分析。治疗方式包括手术、放疗或两者联合。28%的患者为恶性混合瘤，18%为黏液表皮样瘤，15%为腺样囊性瘤，13%为腺泡状瘤，11%为未分化瘤，10%为腺癌，5%为其他类型。10年校正生存率为52%，在以下方面发现了生存率的显著差异：1. 疾病分期为I - IV期的患者（I期：85%，II期：69%，III期：43%，IV期：14%）；2. 有局部肿瘤扩展的患者（34%）和无局部肿瘤扩展的患者（79%）；3. 有面神经麻痹的患者（0%）和无面神经麻痹的患者（57%）；4. 低级别或中级别肿瘤患者（合计69%）和高级别恶性肿瘤患者（30%）。45%的患者在初次治疗后治愈，另外22%接受局部或颈部淋巴结复发治疗的患者也治愈。结论是，UICC 1987年的TNM分类（肿瘤分期和局部扩展）与预后有良好的相关性，并且面神经麻痹和恶性程度是重要的预后因素。
