Chamberland M
Service de Médecine Interne, Centre Hospitalier Universitaire de Sherbrooke, Québec.
Union Med Can. 1993 May-Jun;122(3):201-3.
An increased incidence of cancer has been observed in patients with pemphigus and described mostly since the 1970. Lymphoreticular malignancies and thymomas were the most often reported neoplasms. Paraneoplastic pemphigus is a newly described syndrome with specific characteristics. In this report, a patient with pemphigus and colonic adenocarcinoma is described. In this case, clinical and histologic features suggest the diagnosis of paraneoplastic pemphigus which would be for the first time described in association with colonic adenocarcinoma.
天疱疮患者的癌症发病率有所增加,这一现象自20世纪70年代以来多有描述。淋巴网状系统恶性肿瘤和胸腺瘤是最常报道的肿瘤。副肿瘤性天疱疮是一种新描述的具有特定特征的综合征。在本报告中,描述了一名患有天疱疮和结肠腺癌的患者。在该病例中,临床和组织学特征提示副肿瘤性天疱疮的诊断,这将是首次报道其与结肠腺癌相关。