Rizzo J F, Lessell S
Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts.
Am J Ophthalmol. 1993 Jul 15;116(1):84-7. doi: 10.1016/s0002-9394(14)71749-0.
Tobacco amblyopia, once an important cause of bilateral optic neuropathy, has become so rare in the United States that some investigators doubt its existence. However, we treated two men who appeared to have this disorder. These two patients demonstrate that tobacco amblyopia can develop without malnutrition, alcoholism, or disordered vitamin B12 metabolism. Both patients recovered, one with cessation of smoking and the other with intramuscular administration of hydroxocobalamin despite continued smoking.
烟草性弱视曾是双侧视神经病变的一个重要原因，在美国已变得极为罕见，以至于一些研究者怀疑其是否存在。然而，我们治疗了两名看似患有这种病症的男性。这两名患者表明，烟草性弱视可在不存在营养不良、酗酒或维生素B12代谢紊乱的情况下发生。两名患者均已康复，其中一名通过戒烟康复，另一名尽管继续吸烟，但通过肌肉注射羟钴胺素康复。
