Graham S M, Flowers J L, Scott T R, Bailey R W, Scovill W A, Zucker K A, Imbembo A L
Department of Surgery, University of Maryland School of Medicine, Baltimore.
Ann Surg. 1993 Jul;218(1):61-7. doi: 10.1097/00000658-199307000-00010.
Planned perioperative endoscopic retrograde cholangiography (ERC) and sphincterotomy (ES) for suspected or proven common bile duct stones (CBDS) has been attempted in 63 of 540 consecutive patients undergoing laparoscopic cholecystectomy (LC). Experience with this intervention has been studied with respect to accuracy, efficacy, and safety.
The optimal management of CBDSs in the era of LC is not defined. Methods exist for the laparoscopic manipulation of the common bile duct; however, experience is limited. Until surgeons become comfortable with this more demanding technique, ERC and ES will have a prominent role in the perioperative management of CBDSs.
A preoperative group (n = 41) included all candidates for LC with historical, biochemical, or radiologic evidence of CBDSs. A postoperative LC group (n = 22) included patients with stones diagnosed by intraoperative cholangiogram (IOC) (n = 6) or with signs or symptoms of retained, but unproven, CBDSs (n = 16).
Thirty-six (88%) of the preoperative attempts were successful. Stones were identified in 18 cases and ES and duct clearance were achieved in all 18. In the postoperative group, ERC was successful in 21 (95%) cases. Calculi were demonstrated in 5 of 6 patients with a positive IOC and 6 of 16 with clinically suspected retained stones. ES and duct clearance were achieved in all 11 patients with documented CBDSs. Overall, ERC was accomplished in 90% of cases. Stones were identified in 51% of cases and all stones were cleared by ES. Morbidity was confined to four cases of self-limited pancreatitis (6%). There were no deaths.
The perioperative management of CBDSs is an appealing approach for patients anticipating the benefits of LC, at least until the laparoscopic manipulation of the common bile duct becomes a more widely accepted technique.
在540例连续接受腹腔镜胆囊切除术(LC)的患者中,有63例尝试对疑似或已证实的胆总管结石(CBDS)进行计划性围手术期内镜逆行胆管造影(ERC)和括约肌切开术(ES)。已针对该干预措施的准确性、有效性和安全性进行了研究。
LC时代CBDS的最佳管理方法尚未明确。存在用于腹腔镜操作胆总管的方法;然而,经验有限。在外科医生对这种要求更高的技术熟练掌握之前,ERC和ES在CBDS的围手术期管理中将发挥重要作用。
术前组(n = 41)包括所有有CBDS病史、生化或放射学证据的LC候选患者。术后LC组(n = 22)包括术中胆管造影(IOC)诊断为结石的患者(n = 6)或有保留但未经证实的CBDS体征或症状的患者(n = 16)。
术前尝试中有36例(88%)成功。18例发现结石,所有18例均完成ES并清除胆管结石。在术后组中,ERC在21例(95%)中成功。IOC阳性的6例患者中有5例显示结石,临床怀疑有残留结石的16例中有6例显示结石。所有11例有记录的CBDS患者均完成ES并清除胆管结石。总体而言,90%的病例完成了ERC。51%的病例发现结石,所有结石均通过ES清除。并发症仅限于4例自限性胰腺炎(6%)。无死亡病例。
对于期望从LC中获益的患者,CBDS的围手术期管理是一种有吸引力的方法,至少在腹腔镜操作胆总管成为更广泛接受的技术之前是这样。