Aitkens S G, McCrory M A, Kilmer D D, Bernauer E M
Department of Physical Medicine and Rehabilitation, School of Medicine, University of California, Davis 95616.
Arch Phys Med Rehabil. 1993 Jul;74(7):711-5. doi: 10.1016/0003-9993(93)90031-5.
A 12-week moderate resistance exercise program was performed by 27 patients with slowly progressive neuromuscular diseases (NMD) and 14 control subjects (CTL) in order to determine safety and efficacy of a strengthening program. A 3-day per week submaximal regimen of home exercise using ankle and wrist weights and hand grip exerciser was prescribed. One side of the body was randomly chosen for exercise. Subjects were tested for maximal isokinetic and isometric strength at baseline and after weeks 4 and 12 of the training protocol, and the prescribed amount of work was gradually increased throughout the program. Both the NMD and CTL groups demonstrated significant (p < .05) increases in most strength measures. Both groups responded similarly to the exercise program, and strength gains did not significantly differ between the exercised and nonexercised limbs in either group. This study provides evidence that a 12-week submaximal strength training program is practical and safe in slowly progressive NMD and produces moderate improvement in measured strength.
27 例缓慢进展性神经肌肉疾病（NMD）患者和 14 名对照受试者（CTL）进行了一项为期 12 周的中等强度抗阻运动计划，以确定强化计划的安全性和有效性。规定了每周 3 天的次最大强度家庭锻炼方案，使用脚踝和手腕负重以及握力器。随机选择身体的一侧进行锻炼。在训练方案的基线、第 4 周和第 12 周后，对受试者进行最大等速和等长力量测试，并且在整个计划中逐渐增加规定的运动量。NMD 组和 CTL 组在大多数力量指标上均显示出显著（p <.05）增加。两组对运动计划的反应相似，且两组中运动肢体和未运动肢体的力量增加没有显著差异。本研究提供了证据，表明为期 12 周的次最大强度力量训练计划在缓慢进展性 NMD 中是实用且安全的，并且在测量的力量方面产生了适度改善。
